Nature Structural Biology
4, 167 - 169 (1997)
doi:10.1038/nsb0397-167
Peptide nucleic acids and prebiotic chemistryStanley L. Miller1
1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0506, USA Indentifing the first genetic molecule will provide the key to understanding the origin of life. RNA is an unlikely candidate but peptide nucleic acid looks promising in the role of primordial genetic material. REFERENCES
- Nielsen, P.E., Egholm, M., Berg, R.H., & Buchardt, O. Science 254, 1497−1500 (1991). | PubMed | ISI | ChemPort |
- Egholm, M., Buchardt, O., Nielsen, P.E., & Berg, R.H. J. Am. Chem. Soc. 114, 1895−1897 (1992). | ISI | ChemPort |
- Uhlmann, E. & Peyman, A. Chem. Rev. 90, 543−585 (1990). | ISI | ChemPort |
- De Mesmaeker, A et al. Bull. Soc. Chim. Belg. 103, 705−717 (1994). | ChemPort |
- Sanghvi, Y.S. & Cook, P.D. (eds.) Carbohydrate modifications in antisense research (ACS Symp. 580) American Chemical Society, Washington, D.C. (1994).
- Betts, L., Josey, J.A., Veal, J.M. & Jordan, S.R. Science 270, 1838−1841 (1995). | PubMed | ISI | ChemPort |
- Brown, S.C., Thomson, S.A., Veal, J.M. & Davis, D.G. Science 265, 777−780 (1994). | PubMed | ISI | ChemPort |
- Eriksson, M. & Nielsen, P.E. Nature Struct. Biol. 3, 410−413 (1996). | PubMed | ISI | ChemPort |
- Rasmussen, H., Kastrup, J.S., Nielsen, J.N., Nielsen, J.M. & Nielsen, P.E. Nature Struct. Biol. 4, 98−100 (1997). | PubMed | ISI | ChemPort |
- Pitsch, S., Wendeborn, S., Jaun, B. & Eschenmoser, A. Helv. Chim. Acta 76, 2161−2183 (1993). | ISI | ChemPort |
- Eschenmoser, A. & Loewenthal, E. Chem. Soc. Reviews. 21, 1−16 (1992). | Article | ISI | ChemPort |
- Eschenmoser, A. Origins life Evol. Biosphere 24, 389−423 (1994). | ChemPort |
- Nielsen, P.E. Origins Life Evol. Biosphere 23, 323−327 (1993). | ChemPort |
- Gesteland, R.F. & Atkins, J.F. (eds) The RNA World Cold Spring Harbor Laboratory Press, New York, 1993.
- Orgel, L.E. Cold Spring Harbor Symp. Quant. Biol. 52, 9−16 (1987). | PubMed | ISI | ChemPort |
- Joyce, G.F. Cold Spring Harbor Symp. Quant. Biol. 52, 41−51 (1987). | PubMed | ISI | ChemPort |
- Joyce, G.F., Schwartz, A.W., Miller, S.L. & Orgel, L.E. Proc. Natl. Acad. Sci. USA 84, 4398−4402 (1987). | PubMed | ChemPort |
- Schneider, K.C. & Benner, S.A. J. Am. Chem. Soc. 112, 453−455 (1990). | ISI | ChemPort |
- Fuller, W.D., Sanchez, R.A. & Orgel, L.E. J. Mol. Biol. 67, 25−33 (1972). | PubMed | ISI | ChemPort |
- Fuller, W.D., Sanchez, R.A. & Orgel, L.E. J. Mol. Evol. 1, 249−257 (1972). | PubMed | ISI | ChemPort |
- Müller, D. et al. Helv. Chem. Acta 73, 1410−1468 (1990). | ISI |
- Larralde, R., Robertson, M.P. & Miller, S.L. Proc. Natl. Acad. Sci. USA 92, 8158−8160 (1995). | PubMed | ChemPort |
- Keefe, A.D. & Miller, S.L. J. Molec. Evol. 41, 693−702 (1995). | PubMed | ISI | ChemPort |
- Böhler, C., Nielsen, P.E. & Orgel, L.E. Nature 376, 578−581 (1995). | Article | PubMed | ISI | ChemPort |
|