Nature Structural Biology
4, 877 - 879 (1997)
doi:10.1038/nsb1197-877
Prokaryotes offer hope for potassium channel structural studiesRoderick MacKinnon1, 2
& Declan Anthony Doyle1
1Roderick MacKinnon and Declan Anthony Doyle are at the Laboratory of Molecular Neurobiology and Biophysics, Howard Hughes Medical Institute, Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.
2email: mackinn@rockvax.rockefeller.edu An exciting breakthrough in ion channel studies will be the determination of their structures. A potassium channel structure may be on the horizon.
REFERENCES
- Blattner, F.R. et al. Science 277, 1453−1474 (1997). | Article | PubMed | ISI | ChemPort |
- Bult, C.J. et al. Science 273, 1058−1073 (1996). | PubMed | ISI | ChemPort |
- Hille, B. Ionic Channels Of Excitable Membrances. 1−607 (Sinauer Associates Inc., Sunderland, Massachusetts; 1992).
- Ketchum, K.A., Joiner, W.J., Sellers, A.J., Kaczmarek, L.K. & Goldstein, S.A. Nature 376, 690−695 (1995). | Article | PubMed | ISI | ChemPort |
- Heginbotham, L., Lu, Z., Abramson, T. & MacKinnon, R. Biophys. J. 66, 1061−1067 (1994). | PubMed | ISI | ChemPort |
- Grell, E., Theodor, Funck, T. & Eggers, F. in Membranes, Lipid Bilayers and Biological membranes: Dynamic Properties (ed. Eisenman, G.) 1−126 (Marcel Dekker Inc., New York and Basel; 1975). | ChemPort |
- Hohenester, E., Keller, J.W. & Jansonius, J.N. Biochemistry 33, 13561−13570 (1994). | PubMed | ISI | ChemPort |
- Sunner, J., Nishizawa, K. & Kebarle, P. J. Phys. Chem. 85, 1814−1820 (1981). | ISI | ChemPort |
- Armstrong, C. & Bezanilla, F. Nature 242, 459−461 (1973). | PubMed | ISI | ChemPort |
- Papazian, D.M., Schwarz, T.L., Tempel, B.L., Jan, Y.N. & Jan, L.Y. Science 237, 749−753 (1987). | PubMed | ISI | ChemPort |
- Ho, K. et al. Nature 362, 31−38 (1993). | Article | PubMed | ISI | ChemPort |
- Milkman, R. Proc. Natl. Acad. Sci. USA 91, 3510−3514 (1994). | PubMed | ChemPort |
- Schrempf, H. et al. EMBO J. 14, 5170−5178 (1995). | PubMed | ISI | ChemPort |
|
