Nature Structural Biology
3, 740 - 743 (1996)
doi:10.1038/nsb0996-740
DNA is bound within the central hole to one or two of the six subunits of the T7 DNA helicaseXiong Yu1, Manju M. Hingorani2, Smita S. Patel2
& Edward H. Egelman1
1Department of Cell Biology and Neuroanatomy, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
2Department of Biochemistry, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, USA Electron microscopic image analysis and protein−DNA crosslinking show that DNA binds asymmetrically to the hexameric bacteriophage T7 gp4b helicase, and binds to only one or two subunits
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