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Nature Structural Biology  3, 737 - 739 (1996)
doi:10.1038/nsb0996-737

Myosin isoforms show different strokes for different blokes

Robert J. Barsotti2, Jody A. Dantzig1 & Yale E. Goldman1

  1Department of Physiology, Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6083, USA

  2Bockus Research Institute, Graduate Hospital, Philadelphia, Pennsylvania 19146, USA

Spectroscopic evidence for tilting of smooth muscle, but not skeletal muscle, myosin heads when ADP dissociates suggests mechanisms for the adaptations of these muscle types for their specialized roles.

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