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Correspondence
Nature Structural Biology  3, 668 - 671 (1996)
doi:10.1038/nsb0896-668

A specific structural interaction of Alzheimer's peptide Abold beta1−42 with alpha1-antichymotrypsin

Sabina Janciauskiene1, Sten Eriksson2 & H. Tonie Wright2

  1Department of Medicine, University Hospital of Malmö, Lund University, Malmö 20502, Sweden.

  2Department of Biochemistry and Molecular Biophysics, Virginia Commonwealth University Richmond, Virginia 23298-0614 USA

alpha1-antichymotrypsin and Alzheimer's Abeta1−42 peptide appear to form a complex whose inferred structure suggests possible mechanisms for stimulation of Alzheimer's amyloid fibril formation.

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