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Extending the recognition site of designed minor groove binding molecules

Nature Structural Biology volume 3, pages 321–324 (1996)Cite this article

A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specif icially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode.

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Authors and Affiliations

  1. Department of Chemistry, University of California, Berkeley, California, 94720-1460, USA

    Bernhard H. Geierstanger & David E. Wemmer

  2. Arnold and Mabel Beckman Laboratories of Chemical Synthesis, California Institute of Technology, Pasadena, California, 91125, USA

    Milan Mrksich & Peter B. Dervan

Authors
  1. Bernhard H. Geierstanger
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  2. Milan Mrksich
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  3. Peter B. Dervan
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  4. David E. Wemmer
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Geierstanger, B., Mrksich, M., Dervan, P. et al. Extending the recognition site of designed minor groove binding molecules. Nat Struct Mol Biol 3, 321–324 (1996). https://doi.org/10.1038/nsb0496-321

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