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Nature Structural Biology  3, 977 - 980 (1996)
doi:10.1038/nsb1296-977

Leucines on a roll

Bostjan Kobe1

1St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia. B.Kobe@medidne_stvin.unimelb.edu.au

Several proteins have recently been found to consist of repetitive structural units in a superhelical arrangement. The structure of the leucine-rich repeat variant protein represents an unexpected addition to the list of such proteins, with the repetitive unit consisting of antiparallel alpha- and 310-helices.

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