Provider: Nature Publishing Group
Content: application/x-research-info-systems
TY  - JOUR
AU  - Goetzl, E.J.
AU  - An, S.
AU  - Smith, W.L.
TI  - Specificty of expression and effects of eicosanoid mediators in normal physiology and human diseases
JO  - FASEB J.
PY  - 1995///
VL  - 9
SP  - 1051
EP  - 1058
ER  - 

TY  - GEN
AU  - Smith, W.L.
AU  - Borgeat, P.
AU  - Fitzpatrick, F.A.
TI  - Biochemistry of Lipids, Lipoproteins and Membranes
PY  - 1991///
ER  - 

TY  - JOUR
AU  - Kujubu, D.A.
AU  - Fletcher, B.S.
AU  - Varnum, B.C.
AU  - Lim, R.W.
AU  - Herschman, H.R.
TI  - TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase
JO  - J. Biol. Chem.
PY  - 1991///
VL  - 266
SP  - 12866
EP  - 12872
ER  - 

TY  - JOUR
AU  - Hla, T.
AU  - Neilson, K.
TI  - Human cyclooxygenase-2 cDNA
JO  - Proc. Natl. Acad. Sci., USA
PY  - 1992///
VL  - 89
SP  - 7384
EP  - 7388
ER  - 

TY  - JOUR
AU  - Tazawa, R.
AU  - Xu, X.M.
AU  - Wu, K.K.
AU  - Wang, L.H.
TI  - Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene
JO  - Biochem. Biophys. Res. Comm.
PY  - 1994///
VL  - 203
SP  - 190
EP  - 199
M3  - 10.1006/bbrc.1994.2167
N1  - 10.1006/bbrc.1994.2167
UR  - http://dx.doi.org/10.1006/bbrc.1994.2167
ER  - 

TY  - JOUR
AU  - Goppelt-Struebe, M.
TI  - Regulation of Prostaglandin endoperoxide synthase (Cyclooxygenase) isozyme expression
JO  - Prostagl. Leukotr. Essen. Fatty Acids
PY  - 1995///
VL  - 52
SP  - 213
EP  - 222
M3  - 10.1016/0952-3278(95)90039-X
N1  - 10.1016/0952-3278(95)90039-X
UR  - http://dx.doi.org/10.1016/0952-3278(95)90039-X
ER  - 

TY  - JOUR
AU  - Morita, I.
TI  - Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2
JO  - J. Biol. Chem.
PY  - 1995///
VL  - 270
SP  - 10902
EP  - 10908
M3  - 10.1074/jbc.270.18.10902
N1  - 10.1074/jbc.270.18.10902
UR  - http://dx.doi.org/10.1074/jbc.270.18.10902
ER  - 

TY  - JOUR
AU  - Lassmann, G.
AU  - Odenwaller, R.
AU  - Curtis, J.F.
AU  - DeGray, J.A.
AU  - Mason, R.P.
AU  - Marnett, L.J.
AU  - Eling, T.E.
TI  - Electron spin resonance investigation of tyrosyl radicals of prostaglandin H synthase: Relation to enzyme catalysis
JO  - J. Biol. Chem.
PY  - 1991///
VL  - 266
SP  - 20045
EP  - 2055
ER  - 

TY  - JOUR
AU  - Shimokawa, T.
AU  - Kulmacz, R.J.
AU  - Dewitt, D.L.
AU  - Smith, W.L.
TI  - Tyrosine 385 of prostaglandin endoperoxide synthase is required for cyclooxygenase catalysis
JO  - J. Biol. Chem.
PY  - 1990///
VL  - 265
SP  - 20073
EP  - 20076
ER  - 

TY  - JOUR
AU  - Picot, D.
AU  - Loll, P.J.
AU  - Garavito, R.M.
TI  - The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
JO  - Nature
PY  - 1994///
VL  - 367
SP  - 243
EP  - 249
M3  - 10.1038/367243a0
N1  - 10.1038/367243a0
UR  - http://dx.doi.org/10.1038/367243a0
ER  - 

TY  - JOUR
AU  - Smith, W.L.
AU  - Eling, T.E.
AU  - Kulmacz, R.J.
AU  - Marnett, L.J.
AU  - Tsai, A.
TI  - Tyrosyl radicals and their role in hydroperoxide dependent activation and inactivation of prostaglandin endoperoxide synthase
JO  - Biochem.
PY  - 1992///
VL  - 31
SP  - 3
EP  - 7
ER  - 

TY  - JOUR
AU  - Copeland, R.A.
TI  - Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase
JO  - Proc. Natl. Acad. Sci. USA
PY  - 1994///
VL  - 91
SP  - 11202
EP  - 11206
ER  - 

TY  - GEN
AU  - Garavito, R.M.
TI  - Crystallization of Membrane Proteins
PY  - 1991///
ER  - 

TY  - JOUR
AU  - Barnett, J.
TI  - Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system
JO  - Bioch. Biophys. Acata
PY  - 1994///
VL  - 1209
SP  - 130
EP  - 139
M3  - 10.1016/0167-4838(94)90148-1
N1  - 10.1016/0167-4838(94)90148-1
UR  - http://dx.doi.org/10.1016/0167-4838(94)90148-1
ER  - 

TY  - JOUR
AU  - Hope, H.
TI  - Crystallography of biological macromolecules at ultra-low temperature
JO  - Annu. Rev. Biophys. Biophys. Chem.
PY  - 1990///
VL  - 19
SP  - 107
EP  - 126
M3  - 10.1146/annurev.bb.19.060190.000543
N1  - 10.1146/annurev.bb.19.060190.000543
UR  - http://dx.doi.org/10.1146/annurev.bb.19.060190.000543
ER  - 

TY  - GEN
AU  - Abola, E.E.
AU  - Berstein, F.C.
AU  - Bryant, S.H.
AU  - Koetzle, T.F.
AU  - Weng, J.
TI  - Crystallographk Databases - Information Content, Software Systems, Scientific Applications
PY  - 1987///
ER  - 

TY  - JOUR
AU  - Masferrer, J.L.
TI  - Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulecerogenic
JO  - Proc. Natl. Acad Sci., USA
PY  - 1994///
VL  - 91
SP  - 3228
EP  - 3232
ER  - 

TY  - JOUR
AU  - Garavito, R.M.
AU  - Picot, D.
AU  - Loll, P.J.
TI  - The 3.1 A X-ray crystal structure of the integral membrane enzyme prostaglandin H2 synthase-1
JO  - Adv. Prostagl. Throm. Leukotr. Res.
PY  - 1995///
VL  - 23
SP  - 99
EP  - 103
ER  - 

TY  - JOUR
AU  - Luzzati, V.
TI  - Treatment of statistical errors in the determination of crystal structures
JO  - Acta Crystallogr.
PY  - 1952///
VL  - 5
SP  - 802
EP  - 810
M3  - 10.1107/S0365110X52002161
N1  - 10.1107/S0365110X52002161
UR  - http://dx.doi.org/10.1107/S0365110X52002161
ER  - 

TY  - JOUR
AU  - Loll, P.J.
AU  - Picot, D.
AU  - Ekabo, O.
AU  - Garavito, R.M.
TI  - Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the the prostaglandin H2 cyclooxygenase active site
JO  - Biochem.
PY  - 1996///
VL  - 35
SP  - 7330
EP  - 7340
M3  - 10.1021/bi952776w
N1  - 10.1021/bi952776w
UR  - http://dx.doi.org/10.1021/bi952776w
ER  - 

TY  - JOUR
AU  - Loll, P.J.
AU  - Picot, D.
AU  - Garavito, R.M.
TI  - The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
JO  - Nature Struct. Biol.
PY  - 1995///
VL  - 2
SP  - 637
EP  - 642
ER  - 

TY  - JOUR
AU  - Callan, O.H.
AU  - So, O.
AU  - Swinney, D.
TI  - The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 and 2 by indomethicin and flurbiprofen
JO  - J. Biol.Chem.
PY  - 1996///
VL  - 271
SP  - 3548
EP  - 3554
ER  - 

TY  - JOUR
AU  - Nicholls, A.
AU  - Sharp, K.
AU  - Honig, B.
TI  - Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons
JO  - Proteins
PY  - 1991///
VL  - 11
SP  - 281
EP  - 296
ER  - 

TY  - JOUR
AU  - Gierse, J.K.
TI  - A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors
JO  - J. Biol. Chem.
PY  - 1996///
VL  - 271
SP  - 15810
EP  - 15814
M3  - 10.1074/jbc.271.26.15810
N1  - 10.1074/jbc.271.26.15810
UR  - http://dx.doi.org/10.1074/jbc.271.26.15810
ER  - 

TY  - JOUR
AU  - Laneuville, O.
TI  - Fatty acid substrate specificites of human prostaglandin-enderoxide H synthase-1 and -2
JO  - J. Biol. Chem.
PY  - 1995///
VL  - 270
SP  - 19330
EP  - 19336
M3  - 10.1074/jbc.270.33.19330
N1  - 10.1074/jbc.270.33.19330
UR  - http://dx.doi.org/10.1074/jbc.270.33.19330
ER  - 

TY  - JOUR
AU  - Vane, J.R.
TI  - Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
JO  - Nature New Biol.
PY  - 1971///
VL  - 231
SP  - 232
EP  - 235
ER  - 

TY  - JOUR
AU  - DeWitt, D.L.
TI  - The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases
JO  - J. Biol. Chem.
PY  - 1990///
VL  - 1990
SP  - 5192
EP  - 5198
ER  - 

TY  - JOUR
AU  - Lecomte, M.
AU  - Laneuville, O.
AU  - Ji, C.
AU  - DeWitt, D.L.
AU  - Smith, W.L.
TI  - Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
JO  - J. Biol. Chem.
PY  - 1994///
VL  - 269
SP  - 13207
EP  - 13215
ER  - 

TY  - JOUR
AU  - Mancini, J.A.
AU  - O'eill, G.P.
AU  - Bayly, C.
AU  - Vickers, P.J.
TI  - Mutation of serine-516 in human prostaglandin G/H synthase-2 to methionine and aspirin acetylation of this residue stimulates 15-R-HETE synthesis
JO  - FEBS Lett.
PY  - 1994///
VL  - 342
SP  - 33
EP  - 37
M3  - 10.1016/0014-5793(94)80579-2
N1  - 10.1016/0014-5793(94)80579-2
UR  - http://dx.doi.org/10.1016/0014-5793(94)80579-2
ER  - 

TY  - GEN
AU  - McPherson, A.
TI  - Preparation and analysis of protein crystals
PY  - 1982///
ER  - 

TY  - GEN
AU  - Otwinowski, Z.
TI  - Proc. CCP4 Study Weekend, 29-30 Jan 1991. Data collection and processing
PY  - 1993///
ER  - 

TY  - JOUR
TI  - The CCP4 suite: Programs for protein crystallography
JO  - Acta Cryst.
PY  - 1994///
VL  - D50
SP  - 760
EP  - 763
ER  - 

TY  - GEN
AU  - Brunger, A.T.
TI  - X-PLOR: Version 3.1
PY  - 1987///
ER  - 

TY  - JOUR
AU  - Bernstein, F.C.
TI  - The protein data bank: A computer-based archival file for macromolecular structures
JO  - J. Mol. Biol.
PY  - 1977///
VL  - 112
SP  - 535
EP  - 542
ER  - 

TY  - JOUR
AU  - Brunger, A.T.
TI  - Extension of molecular replacment:. A new search strategy based on Patterson correlation refinement
JO  - Acta Crystallogr.
PY  - 1990///
VL  - A45
SP  - 46
EP  - 57
ER  - 

TY  - JOUR
AU  - Brunger, A.T.
TI  - The free R value: a novel statistical quantity for assessing the accuracy of crystal structures
JO  - Nature
PY  - 1992///
VL  - 355
SP  - 472
EP  - 474
M3  - 10.1038/355472a0
N1  - 10.1038/355472a0
UR  - http://dx.doi.org/10.1038/355472a0
ER  - 

TY  - JOUR
AU  - Muller, K.
TI  - MOLOC: A molecular modeling program
JO  - Bull. Soc. Chim. Belg.
PY  - 1988///
VL  - 97
SP  - 655
EP  - 667
ER  - 

TY  - JOUR
AU  - Browner, M.F.
AU  - Fauman, E.B.
AU  - Fletterick, R.J.
TI  - Tracking conformational states in allosteric transitions of phosphorylase
JO  - Biochemistry
PY  - 1992///
VL  - 31
SP  - 11297
EP  - 11304
ER  - 

TY  - JOUR
AU  - Kraulis, P.
TI  - MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
JO  - J. App. Crystallgr.
PY  - 1991///
VL  - 24
SP  - 946
EP  - 950
M3  - 10.1107/S0021889891004399
N1  - 10.1107/S0021889891004399
UR  - http://dx.doi.org/10.1107/S0021889891004399
ER  - 

TY  - JOUR
AU  - Bacon, D.J.
AU  - Anderson, W.F.
TI  - A fast algorithm for rendering space-filling molecule pictures
JO  - J. Molec. Graph.
PY  - 1988///
VL  - 6
SP  - 219
EP  - 220
M3  - 10.1016/S0263-7855(98)80030-1
N1  - 10.1016/S0263-7855(98)80030-1
UR  - http://dx.doi.org/10.1016/S0263-7855(98)80030-1
ER  - 

