Yeast cells display synchronized oscillation between phases of high and low oxygen consumption accompanied by a program of cyclical gene expression. A study monitoring mRNA levels, histone modifications and chromatin occupancy of histone modifiers during the yeast metabolic cycle (YMC) at high temporal resolution reveals both 'just-in-time' supply of YMC gene products and new patterns of chromatin reconfiguration associated with transcriptional regulation.
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Friis, R., Schultz, M. The timing is right. Nat Struct Mol Biol 21, 846–847 (2014). https://doi.org/10.1038/nsmb.2898
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DOI: https://doi.org/10.1038/nsmb.2898