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NHEJ and its backup pathways in chromosomal translocations

Two recent papers break major new ground on the issues of NHEJ, backup pathways for NHEJ and how these relate to the chromosomal translocation process.

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Figure 1: Components of NHEJ and candidates for alternative pathways.
Figure 2: Two possible relationships between NHEJ and alternative end-joining pathways.

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Correspondence to Michael R Lieber.

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Lieber, M. NHEJ and its backup pathways in chromosomal translocations. Nat Struct Mol Biol 17, 393–395 (2010). https://doi.org/10.1038/nsmb0410-393

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