About the cover

February 2010 Volume 17 No 2

CDK8, found in some Mediator complexes, is now shown to be a positive regulator of transcription elongation, as opposed to initiation, at immediate early serum response genes. The image conveys the connection of the different factors in an unexpected arrangement. Based on an idea from J. Espinosa and Lacey Coover, original artwork by Colleen Buzzard (http://www.colleenbuzzard.com). pp 194-201