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January 2010 Volume 17 No 1

MicroRNAs are regulators of gene expression that have been identified in many species. Kai and Pasquinelli now review and discuss recent work showing that microRNA turnover is regulated, forming part of our web focus on RNA silencing (http://www.nature.com/nsmb/focus/rnasilencing). The cover, "Degradation," is original artwork by Colleen Buzzard (http://www.colleenbuzzard.com). pp 5-10

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