Male fruitflies upregulate transcription of nearly all genes on their single X chromosome to equalize expression with the two X chromosomes in females. A new study shows that the distribution of the histone acetylation mark associated with this upregulation is much broader than that of the MSL complex responsible for depositing this mark.
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Weake, V., Workman, J. Hit and run: X marks the spot!. Nat Struct Mol Biol 16, 801–803 (2009). https://doi.org/10.1038/nsmb0809-801
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DOI: https://doi.org/10.1038/nsmb0809-801