News and Views
Nature Structural & Molecular Biology 15, 779 - 781 (2008)
doi:10.1038/nsmb0808-779
A splicing regulator promotes transcriptional elongation
Juan Pablo Fededa1 & Alberto R Kornblihtt1
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Juan Pablo Fededa and Alberto R. Kornblihtt are at the Laboratorio de Fisiología y Biología Molecular, IFIByNE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
e-mail: ark@fbmc.fcen.uba.ar
Abstract
A new study reveals that the serine/arginine-rich splicing factor SC35 is necessary to promote RNA polymerase II elongation in a subset of genes, confirming a bidirectional coupling between transcription and splicing.
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