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Nature Structural & Molecular Biology 15, 538–540 (1 June 2008) | doi:10.1038/nsmb0608-538
How is SOS activated? Let us count the ways
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Abstract
External signals stimulate pathways that control cellular functions such as proliferation, migration, survival and metabolism. Such signaling events therefore have profound biological consequences, and their aberrant activation can induce malignant transformation or developmental defects.
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