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Brief Communication
Nature Structural & Molecular Biology 15, 534–536 (1 May 2008) | doi:10.1038/nsmb.1408
A conserved rRNA methyltransferase regulates ribosome biogenesis
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Abstract
In contrast to the diversity of most ribosomal RNA modification patterns and systems, the KsgA methyltransferase family seems to be nearly universally conserved along with the modifications it catalyzes. Our data reveal that KsgA interacts with small ribosomal subunits near functional sites, including Initiation factor 3 and 50S subunit binding sites.
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