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Nature Structural & Molecular Biology 15, 428 - 430 (2008)
doi:10.1038/nsmb0508-428
The type II secretion arrowhead: the structure of GspI–GspJ–GspK
Katrina T Forest1
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Katrina T. Forest is at the Department of Bacteriology, University of Wisconsin-Madison, 1550 Linden Drive, Madison, Wisconsin 53706, USA.
e-mail: forest@bact.wisc.edu
Abstract
A heterotrimeric complex of minor pseudopilins from the type II secretion system has been identified and its crystal structure solved. Although each subunit shares the same overall
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fold as other characterized (pseudo)pilins, GspK has a unique large
-helical domain inserted between two canonical
-strands. The structure constrains models for pseudopilus assembly.
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