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Nature Structural & Molecular Biology 15, 127 - 128 (2008)
doi:10.1038/nsmb0208-127
Energizing type III secretion machines: what is the fuel?
Jorge E. Galán1
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Jorge E. Galán is at the Section of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, Connecticut 06536, USA.
e-mail: jorge.galan@yale.edu
Abstract
Bacterial type III secretion machines have adapted to carry out numerous functions, ranging from locomotion to protein delivery into nucleated cells. One of the most intriguing issues is the source of energy that fuels their activities. Despite recent advances, there are still many questions to be resolved.
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