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Nature Structural & Molecular Biology 15, 1243–1244 (1 December 2008) | doi:10.1038/nsmb1208-1243

PARP: a transferase by any other name

Susanne Till , Konstantina Diamantara & Andreas G Ladurner

Chris Walsh's landmark textbook on the post-translational modification (PTM) of proteins contains a precious, slender chapter on ADP-ribosylation. For decades, this field has been dominated by two classes of NAD+-metabolizing enzymes, PARP1 and the extracellular mono-ADP-ribosyltransferases (mARTs).