News and Views
Nature Structural & Molecular Biology 15, 1243 - 1244 (2008)
doi:10.1038/nsmb1208-1243
PARP: a transferase by any other name
Susanne Till1, Konstantina Diamantara1 & Andreas G Ladurner1
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Susanne Till, Konstantina Diamantara and Andreas G. Ladurner are in the Gene Expression Unit and Structural & Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
e-mail: ladurner@embl.de
Abstract
A recent report shows that several 'poly-ADP-ribose-polymerases' may function exclusively as a family of endogenous mono-ADP-ribosyltransferases, providing a new, molecularly less complex and broadened cellular role for this elusive post-translational modification.
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