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Nature Structural & Molecular Biology 14, 792–794 (1 September 2007) | doi:10.1038/nsmb0907-792
Chloride finds its place in the transport cycle
Abstract
Neurons and glial cells accumulate neurotransmitters by a sodium-coupled transport process that is in many respects similar to systems used by other cells and organisms for concentrating amines and amino acids. By cotransporting a solute with one or more sodium ions, the energy stored in the transmembrane electrochemical gradient can be harnessed to drive the solute into the cell.
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