Supplementary information
From the following article
Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
Baisong Liao, Yan Hu & Gary Brewer
Nature Structural & Molecular Biology 14, 511 - 518 (2007) Published online: 7 May 2007 Corrected online: 21 May 2007
doi:10.1038/nsmb1249
Supplementary Fig. 1
Antibody specific for AUF1 precipitates MYC mRNA from cytoplasmic lysates of K562 cells
Supplementary Fig. 2
Effects of AUF1 knockdown on MYC gene expression in HeLa cells
Supplementary Fig. 3
Effects of AUF1 knockdown on luciferase-MYC ARE reporter gene expression in HeLa cells
Supplementary Fig. 4
TIAR antibody precipitates MYC ARE reporter mRNA but not luciferase mRNA lacking the ARE
Supplementary Fig. 5
TIAR knockdown has no effect on MYC mRNA levels in K562 cells
Supplementary Fig. 6
Effects of TIAR knockdown on luciferase–MYC ARE reporter gene expression with in K562 cells
Supplementary Fig. 7
Controls for mRNP immunoprecipitations following AUF1 and TIAR knockdown
Supplementary Fig. 8
AUF1 knockdown retards proliferation of HeLa cells
Supplementary Fig. 9
TIAR knockdown reverses the cellular proliferation defect conferred by AUF1 knockdown
Supplementary Fig. 10
MYC knockdown reverses the proliferation-inducing effects of TIAR knockdown
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