New data, please - p457

doi:10.1038/nsmb0607-457

Full Text - New data, please | PDF (235 KB) - New data, please

Protein structure space is much more than the sum of its folds - p458

Barry Honig

doi:10.1038/nsmb0607-458

Full Text - Protein structure space is much more than the sum of its folds | PDF (52 KB) - Protein structure space is much more than the sum of its folds

Protein Structure Initiative: getting into gear - pp459 - 460

Brian W Matthews

doi:10.1038/nsmb0607-459

Full Text - Protein Structure Initiative: getting into gear | PDF (3,945 KB) - Protein Structure Initiative: getting into gear

RAD51, BRCA2 and DNA repair: a partial resolution - pp461 - 462

Christopher J Lord & Alan Ashworth

doi:10.1038/nsmb0607-461

Full Text - RAD51, BRCA2 and DNA repair: a partial resolution | PDF (198 KB) - RAD51, BRCA2 and DNA repair: a partial resolution

See also: Article by Esashi et al. | Article by Davies & Pellegrini

It takes more than two to tango: Dishevelled polymerization and Wnt signaling - pp463 - 465

David M Roberts, Kevin C Slep & Mark Peifer

doi:10.1038/nsmb0607-463

Full Text - It takes more than two to tango: Dishevelled polymerization and Wnt signaling | PDF (2,515 KB) - It takes more than two to tango: Dishevelled polymerization and Wnt signaling

See also: Article by Schwarz-Romond et al.

Moving parts: how the adaptor protein CRK is regulated, and regulates - pp465 - 466

David Cowburn

doi:10.1038/nsmb0607-465

Full Text - Moving parts: how the adaptor protein CRK is regulated, and regulates | PDF (214 KB) - Moving parts: how the adaptor protein CRK is regulated, and regulates

See also: Article by Kobashigawa et al.

Research highlights - p467

doi:10.1038/nsmb0607-467

Full Text - Research highlights | PDF (267 KB) - Research highlights

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2 - pp468 - 474

Fumiko Esashi, Vitold E Galkin, Xiong Yu, Edward H Egelman & Stephen C West

doi:10.1038/nsmb1245

Abstract - Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2 | Full Text - Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2 | PDF (406 KB) - Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2

See also: News and Views by Lord & Ashworth

Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats - pp475 - 483

Owen Richard Davies & Luca Pellegrini

doi:10.1038/nsmb1251

Abstract - Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats | Full Text - Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats | PDF (676 KB) - Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats | Supplementary information

See also: News and Views by Lord & Ashworth

The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization - pp484 - 492

Thomas Schwarz-Romond, Marc Fiedler, Naoki Shibata, P Jonathan G Butler, Akira Kikuchi, Yoshiki Higuchi & Mariann Bienz

doi:10.1038/nsmb1247

• PDB code

  • 1WSP

• 3D view

  • 1WSP

Abstract - The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization | Full Text - The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization | PDF (723 KB) - The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization | Supplementary information

See also: News and Views by Roberts et al.

The antibiotic viomycin traps the ribosome in an intermediate state of translocation - pp493 - 497

Dmitri N Ermolenko, P Clint Spiegel, Zigurts K Majumdar, Robyn P Hickerson, Robert M Clegg & Harry F Noller

doi:10.1038/nsmb1243

Abstract - The antibiotic viomycin traps the ribosome in an intermediate state of translocation | Full Text - The antibiotic viomycin traps the ribosome in an intermediate state of translocation | PDF (297 KB) - The antibiotic viomycin traps the ribosome in an intermediate state of translocation | Supplementary information

Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines - pp498 - 502

Albert Weixlbaumer, Frank V Murphy, IV, Agnieszka Dziergowska, Andrzej Malkiewicz, Franck A P Vendeix, Paul F Agris & V Ramakrishnan

doi:10.1038/nsmb1242

• PDB code

  • 2UU9
  • 2UUA
  • 2UUB
  • 2UUC

• 3D view

  • 2UU9
  • 2UUA
  • 2UUB
  • 2UUC

Abstract - Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines | Full Text - Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines | PDF (344 KB) - Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines | Supplementary information

Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK - pp503 - 510

Yoshihiro Kobashigawa, Mieko Sakai, Masato Naito, Masashi Yokochi, Hiroyuki Kumeta, Yoshinori Makino, Kenji Ogura, Shinya Tanaka & Fuyuhiko Inagaki

doi:10.1038/nsmb1241

• PDB code

  • 2EYV
  • 2EYW
  • 2EYX
  • 2EYY
  • 2EYZ
  • 2DVJ

• 3D view

  • 2EYV
  • 2EYW
  • 2EYX
  • 2EYY
  • 2EYZ
  • 2DVJ

Abstract - Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK | Full Text - Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK | PDF (2,425 KB) - Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK | Supplementary information

See also: News and Views by Cowburn

Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation - pp511 - 518

Baisong Liao, Yan Hu & Gary Brewer

doi:10.1038/nsmb1249

Abstract - Competitive binding of AUF1 and TIAR to : MYC: mRNA controls its translation | Full Text - Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation | PDF (305 KB) - Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation | Supplementary information

Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing - pp519 - 526

Li Liu, Charles C Query & Maria M Konarska

doi:10.1038/nsmb1240

Abstract - Opposing classes of : prp8: alleles modulate the transition between the catalytic steps of pre-mRNA splicing | Full Text - Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing | PDF (483 KB) - Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing

Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40 - pp527 - 534

Yu Chen, Yanhui Xu, Qing Bao, Yongna Xing, Zhu Li, Zheng Lin, Jeffry B Stock, Philip D Jeffrey & Yigong Shi

doi:10.1038/nsmb1254

• PDB code

  • 2PKG

• 3D view

  • 2PKG

Abstract - Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40 | Full Text - Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40 | PDF (596 KB) - Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40

Structural basis of histone demethylation by LSD1 revealed by suicide inactivation - pp535 - 539

Maojun Yang, Jeffrey C Culhane, Lawrence M Szewczuk, Christian B Gocke, Chad A Brautigam, Diana R Tomchick, Mischa Machius, Philip A Cole & Hongtao Yu

doi:10.1038/nsmb1255

• PDB code

  • 2UXN

• 3D view

  • 2UXN

Abstract - Structural basis of histone demethylation by LSD1 revealed by suicide inactivation | Full Text - Structural basis of histone demethylation by LSD1 revealed by suicide inactivation | PDF (422 KB) - Structural basis of histone demethylation by LSD1 revealed by suicide inactivation | Supplementary information

Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement - pp540 - 547

Xiaofang Yang, Roser Zaurin, Miguel Beato & Craig L Peterson

doi:10.1038/nsmb1238

Abstract - Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement | Full Text - Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement | PDF (395 KB) - Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement | Supplementary information

SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery - pp548 - 555

Matthew J Gamble & Robert P Fisher

doi:10.1038/nsmb1248

Abstract - SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery | Full Text - SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery | PDF (320 KB) - SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery | Supplementary information

The redox-switch domain of Hsp33 functions as dual stress sensor - pp556 - 563

Marianne Ilbert, Janina Horst, Sebastian Ahrens, Jeannette Winter, Paul C F Graf, Hauke Lilie & Ursula Jakob

doi:10.1038/nsmb1244

Abstract - The redox-switch domain of Hsp33 functions as dual stress sensor | Full Text - The redox-switch domain of Hsp33 functions as dual stress sensor | PDF (448 KB) - The redox-switch domain of Hsp33 functions as dual stress sensor | Supplementary information

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway - pp564 - 567

Ashley E Sims, Elizabeth Spiteri, Robert J Sims, III, Adriana G Arita, Francis P Lach, Thomas Landers, Melanie Wurm, Marcel Freund, Kornelia Neveling, Helmut Hanenberg, Arleen D Auerbach & Tony T Huang

doi:10.1038/nsmb1252

Abstract - FANCI is a second monoubiquitinated member of the Fanconi anemia pathway | Full Text - FANCI is a second monoubiquitinated member of the Fanconi anemia pathway | PDF (371 KB) - FANCI is a second monoubiquitinated member of the Fanconi anemia pathway | Supplementary information

Erratum: The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model - p568

Pingwei Li, Kathryn E Huey-Tubman, Tiyu Gao, Xiaojun Li, Anthony P West, Jr, Melanie J Bennett & Pamela J Bjorkman

doi:10.1038/nsmb0607-568a

Full Text - Erratum: The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model | PDF (55 KB) - Erratum: The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model

Corrigendum: Shifting nanoscopic clock gears - p568

Susan S Golden, Vincent M Cassone & Andy LiWang

doi:10.1038/nsmb0607-568b

Full Text - Corrigendum: Shifting nanoscopic clock gears | PDF (55 KB) - Corrigendum: Shifting nanoscopic clock gears

Corrigendum: FtsK: A groovy helicase - p568

Terence R Strick & Audrey Quessada-Vial

doi:10.1038/nsmb0607-568c

Full Text - Corrigendum: FtsK: A groovy helicase | PDF (55 KB) - Corrigendum: FtsK: A groovy helicase