Contributing more to science - p353

doi:10.1038/nsmb0507-353

Full Text - Contributing more to science | PDF (80 KB) - Contributing more to science

Building meaningful models of glycoproteins - p354

Max Crispin, David I. Stuart & E. Yvonne Jones

doi:10.1038/nsmb0507-354a

Full Text - Building meaningful models of glycoproteins | PDF (85 KB) - Building meaningful models of glycoproteins

Reply to: Building meaningful models of glycoproteins - pp354 - 355

Helen M. Berman, Kim Henrick, Haruki Nakamura & John Markley

doi:10.1038/nsmb0507-354b

Full Text - Reply to: Building meaningful models of glycoproteins | PDF (85 KB) - Reply to: Building meaningful models of glycoproteins

A leak in the EAATs - pp356 - 357

Christopher Miller

doi:10.1038/nsmb0507-356

Full Text - A leak in the EAATs | PDF (416 KB) - A leak in the EAATs

See also: Article by Ryan & Mindell

SIN-fully silent: HDAC complexes in fission yeast - pp358 - 359

Assen Roguev & Nevan J Krogan

doi:10.1038/nsmb0507-358

Full Text - SIN-fully silent: HDAC complexes in fission yeast | PDF (361 KB) - SIN-fully silent: HDAC complexes in fission yeast

See also: Article by Nicolas et al.

Budding insights on cell polarity - pp360 - 362

Dirk Fasshauer & Reinhard Jahn

doi:10.1038/nsmb0507-360

Full Text - Budding insights on cell polarity | PDF (1,175 KB) - Budding insights on cell polarity

Shifting nanoscopic clock gears - pp362 - 363

Susan S Golden, Vincent M Cassone & Andy LiWang

doi:10.1038/nsmb0507-362

Full Text - Shifting nanoscopic clock gears | PDF (805 KB) - Shifting nanoscopic clock gears

Research highlights - p364

doi:10.1038/nsmb0507-364

Full Text - Research highlights | PDF (80 KB) - Research highlights

The uncoupled chloride conductance of a bacterial glutamate transporter homolog - pp365 - 371

Renae M Ryan & Joseph A Mindell

doi:10.1038/nsmb1230

Abstract - The uncoupled chloride conductance of a bacterial glutamate transporter homolog | Full Text - The uncoupled chloride conductance of a bacterial glutamate transporter homolog | PDF (309 KB) - The uncoupled chloride conductance of a bacterial glutamate transporter homolog | Supplementary information

See also: News and Views by Miller

Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection - pp372 - 380

Estelle Nicolas, Takatomi Yamada, Hugh P Cam, Peter C FitzGerald, Ryuji Kobayashi & Shiv I S Grewal

doi:10.1038/nsmb1239

Abstract - Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection | Full Text - Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection | PDF (538 KB) - Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection | Supplementary information

See also: News and Views by Roguev & Krogan

The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model - pp381 - 387

Pingwei Li, Kathryn E Huey-Tubman, Tiyu Gao, Xiaojun Li, Anthony P West, Jr, Melanie J Bennett & Pamela J Bjorkman

doi:10.1038/nsmb1234

• PDB code

  • 2GSG
  • 2OTU
  • 2OTW

• 3D view

  • 2GSG
  • 2OTU
  • 2OTW

Abstract - The structure of a : : polyQ: : -: : anti-polyQ: : complex reveals binding according to a linear lattice model | Full Text - The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model | PDF (655 KB) - The structure of a polyQ–anti-polyQ complex reveals binding according to a linear lattice model | Supplementary information

Structure of the human GINS complex and its assembly and functional interface in replication initiation - pp388 - 396

Katsuhiko Kamada, Yumiko Kubota, Toshiaki Arata, Yosuke Shindo & Fumio Hanaoka

doi:10.1038/nsmb1231

• PDB code

  • 2E9X

• 3D view

  • 2E9X

Abstract - Structure of the human GINS complex and its assembly and functional interface in replication initiation | Full Text - Structure of the human GINS complex and its assembly and functional interface in replication initiation | PDF (753 KB) - Structure of the human GINS complex and its assembly and functional interface in replication initiation | Supplementary information

Homology-driven chromatin remodeling by human RAD54 - pp397 - 405

Zhaoqing Zhang, Hua-Ying Fan, Joseph A Goldman & Robert E Kingston

doi:10.1038/nsmb1223

Abstract - Homology-driven chromatin remodeling by human RAD54 | Full Text - Homology-driven chromatin remodeling by human RAD54 | PDF (444 KB) - Homology-driven chromatin remodeling by human RAD54 | Supplementary information

Structural basis for Rab GTPase activation by VPS9 domain exchange factors - pp406 - 412

Anna Delprato & David G Lambright

doi:10.1038/nsmb1232

• PDB code

  • 2OT3

• 3D view

  • 2OT3

Abstract - Structural basis for Rab GTPase activation by VPS9 domain exchange factors | Full Text - Structural basis for Rab GTPase activation by VPS9 domain exchange factors | PDF (459 KB) - Structural basis for Rab GTPase activation by VPS9 domain exchange factors | Supplementary information

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia - pp413 - 419

David Cunningham, Dennis E Danley, Kieran F Geoghegan, Matthew C Griffor, Julie L Hawkins, Timothy A Subashi, Alison H Varghese, Mark J Ammirati, Jeffrey S Culp, Lise R Hoth, Mahmoud N Mansour, Katherine M McGrath, Andrew P Seddon, Shirish Shenolikar, Kim J Stutzman-Engwall, Laurie C Warren, Donghui Xia & Xiayang Qiu

doi:10.1038/nsmb1235

• PDB code

  • 2P4E

• 3D view

  • 2P4E

Abstract - Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia | Full Text - Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia | PDF (667 KB) - Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia | Supplementary information

Iron-regulatory proteins limit hypoxia-inducible factor-2 expression in iron deficiency - pp420 - 426

Mayka Sanchez, Bruno Galy, Martina U Muckenthaler & Matthias W Hentze

doi:10.1038/nsmb1222

Abstract - Iron-regulatory proteins limit hypoxia-inducible factor-2[alpha] expression in iron deficiency | Full Text - Iron-regulatory proteins limit hypoxia-inducible factor-2 expression in iron deficiency | PDF (361 KB) - Iron-regulatory proteins limit hypoxia-inducible factor-2 expression in iron deficiency | Supplementary information

Structural basis of Na⁺/K⁺-ATPase adaptation to marine environments - pp427 - 431

Claudia Colina, Joshua J C Rosenthal, Joseph A DeGiorgis, Deepa Srikumar, Nikhila Iruku & Miguel Holmgren

doi:10.1038/nsmb1237

Abstract - Structural basis of Na: +: /K: +: -ATPase adaptation to marine environments | Full Text - Structural basis of Na+/K+-ATPase adaptation to marine environments | PDF (331 KB) - Structural basis of Na+/K+-ATPase adaptation to marine environments | Supplementary information

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins - pp432 - 440

Stefanie Reissmann, Charles Parnot, Christopher R Booth, Wah Chiu & Judith Frydman

doi:10.1038/nsmb1236

Abstract - Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins | Full Text - Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins | PDF (390 KB) - Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins | Supplementary information

H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing - pp441 - 448

Emeline Bouffartigues, Malcolm Buckle, Cyril Badaut, Andrew Travers & Sylvie Rimsky

doi:10.1038/nsmb1233

Abstract - H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing | Full Text - H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing | PDF (406 KB) - H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing | Supplementary information

Bluetongue virus VP4 is an RNA-capping assembly line - pp449 - 451

Geoff Sutton, Jonathan M Grimes, David I Stuart & Polly Roy

doi:10.1038/nsmb1225

• PDB code

  • 2JHP
  • 2JH8
  • 2JH9
  • 2JHA
  • 2JHC

• 3D view

  • 2JHP
  • 2JH8
  • 2JH9
  • 2JHA
  • 2JHC

Abstract - Bluetongue virus VP4 is an RNA-capping assembly line | Full Text - Bluetongue virus VP4 is an RNA-capping assembly line | PDF (450 KB) - Bluetongue virus VP4 is an RNA-capping assembly line | Supplementary information

Structure-based design of a pathway-specific nuclear import inhibitor - pp452 - 454

Ahmet E Cansizoglu, Brittany J Lee, Zi Chao Zhang, Beatriz M A Fontoura & Yuh Min Chook

doi:10.1038/nsmb1229

• PDB code

  • 2OT8

• 3D view

  • 2OT8

Abstract - Structure-based design of a pathway-specific nuclear import inhibitor | Full Text - Structure-based design of a pathway-specific nuclear import inhibitor | PDF (298 KB) - Structure-based design of a pathway-specific nuclear import inhibitor | Supplementary information

Corrigendum: Structural basis for autoinhibition of Notch - p455

Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster & Stephen C Blacklow

doi:10.1038/nsmb0507-455

Full Text - Corrigendum: Structural basis for autoinhibition of Notch | PDF (56 KB) - Corrigendum: Structural basis for autoinhibition of Notch