News and Views


Nature Structural & Molecular Biology 14, 360 - 362 (2007)
doi:10.1038/nsmb0507-360

Budding insights on cell polarity

Dirk Fasshauer1 & Reinhard Jahn1

  1. Dirk Fasshauer and Reinhard Jahn are in the Department of Neurobiology, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
    e-mail: dfassha@gwdg.de
    e-mail: rjahn@gwdg.de


The yeast proteins Sro7 and Sro77, and their metazoan relatives Lgl and tomosyn, interact with plasma membrane SNARE proteins and control cell polarity. Recently, the crystal structure of yeast Sro7 has been solved, yielding fascinating insights and even more unanswered questions concerning the molecular mechanism of these proteins.

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