News and Views
Nature Structural & Molecular Biology 14, 259 - 260 (2007)
doi:10.1038/nsmb0407-259
A marked end
Xuemei Chen1
- Xuemei Chen is in the Department of Botany and Plant Sciences, University of California, Riverside, California 92521, USA. e-mail: xuemei.chen@ucr.edu
Abstract
microRNAs (miRNAs) and small interfering RNAs from plants are 2'-O-methylated at their 3' termini. Although miRNAs from animals are not methylated, two studies show that the recently identified mammalian Piwi-interacting RNAs carry a 2'-O-methyl group on the 3' terminal ribose.
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