Supplementary information
From the following article
Structure of a VEGF–VEGF receptor complex determined by electron microscopy
Claudia Ruch, Georgios Skiniotis, Michel O Steinmetz, Thomas Walz & Kurt Ballmer-Hofer
Nature Structural & Molecular Biology 14, 249 - 250 (2007) Published online: 11 February 2007
doi:10.1038/nsmb1202
Supplementary Fig. 1
Schematic representation of VEGFR-2 ECD constructs
Supplementary Fig. 2
Biochemical analysis of VEGFR-2 ECDs and VEGFR-2 ECD?ligand
Supplementary Fig. 3
Raw image of monomeric VEGFR-2 ECD in negative stain
Supplementary Fig. 4
Raw image of predimerized VEGFR-2 ECD GCN4 in negative stain
Supplementary Fig. 5
Raw image of negatively stained predimerized VEGFR-2 ECD GCN4 in complex with VEGF-A
Supplementary Fig. 6
Raw image of negatively stained monomeric VEGFR-2 ECD in complex with VEGF-A
Supplementary Fig. 7
Class averages of predimerized VEGFR-2 ECD GCN4 in complex with VEGF-A
Supplementary Fig. 8
Class averages of monomeric VEGFR-2 ECD in complex with VEGF-A
Supplementary Fig. 9
Raw image of negatively stained monomeric VEGFR-2 ECD in which immunoglobulin-like domain 7 was substituted by immunoglobulin-like domain 6 of VEGFR-1, in complex with VEGF-A
Supplementary Fig. 10
Class averages of monomeric VEGFR-2 ECD in which immunoglobulin-like domain 7 was substituted by immunoglobulin-like domain 6 of VEGFR-1, in complex with VEGF-A
Supplementary Table 1
Complex formation between VEGFR-2 and VEGF ligands
Supplementary Methods
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