Faced with the thermodynamic and kinetic challenge of finding a few specific sites on DNA among millions of nonspecific sites, within a limited amount of time, what's a protein to do? Single-molecule studies show that some proteins have selected sliding on DNA as a solution.
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References
Wagner, R. Jr. & Meselson, M. Proc. Natl. Acad. Sci. USA 73, 4135–4139 (1976).
Iyer, R.R., Pluciennik, A., Burdett, V. & Modrich, P.L. Chem. Rev. 106, 302–323 (2006).
Kunkel, T.A. & Erie, D.A. Annu. Rev. Biochem. 74, 681–710 (2005).
Jiricny, J. Nat. Rev. Mol. Cell Biol. 7, 335–346 (2006).
Obmolova, G., Ban, C., Hsieh, P. & Yang, W. Nature 407, 703–710 (2000).
Lamers, M.H. et al. Nature 407, 711–717 (2000).
Warren, J.J. et al. Mol. Cell 26, 579–592 (2007).
Wang, H. et al. Proc. Natl. Acad. Sci. USA 100, 14822–14827 (2003).
Jiang, J. et al. Mol. Cell 20, 771–781 (2005).
Mazur, D.J., Mendillo, M.L. & Kolodner, R.D. Mol. Cell 22, 39–49 (2006).
Gradia, S. et al. Mol. Cell 3, 255–261 (1999).
Antony, E. & Hingorani, M.M. Biochemistry 42, 7682–7693 (2003).
Kunkel, T.A. & Bebenek, K. Annu. Rev. Biochem. 69, 497–529 (2000).
Gorman, J. et al. Mol. Cell 28, 359–370 (2007).
Shell, S.S., Putnam, C.D. & Kolodner, R.D. Mol. Cell 26, 565–578 (2007).
Junop, M.S., Obmolova, G., Rausch, K., Hsieh, P. & Yang, W. Mol. Cell 7, 1–12 (2001).
Jacobs-Palmer, E. & Hingorani, M.M. J. Mol. Biol. 366, 1087–1098 (2007).
Antony, E. & Hingorani, M.M. Biochemistry 43, 13115–13128 (2004).
Kadyrov, F.A. et al. J. Biol. Chem. doi:10.1074/jbc.M707617200 (published online 19 October 2007).
Pluciennik, A. & Modrich, P. Proc. Natl. Acad. Sci. USA 104, 12709–12713 (2007).
Acharya, S., Foster, P.L., Brooks, P. & Fishel, R. Mol. Cell 12, 233–246 (2003).
Wang, H. & Hays, J.B. Nucleic Acids Res. doi:10.1093/nar/gkm734 (published online 4 October 2007).
Blainey, P.C., van Oijen, A.M., Banerjee, A., Verdine, G.L. & Xie, X.S. Proc. Natl. Acad. Sci. USA 103, 5752–5757 (2006).
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Hingorani, M. TIRF(ing) reveals Msh2-Msh6 surfing on DNA. Nat Struct Mol Biol 14, 1124–1125 (2007). https://doi.org/10.1038/nsmb1207-1124
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DOI: https://doi.org/10.1038/nsmb1207-1124