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Nature Structural & Molecular Biology 14, 1122 - 1123 (2007)
doi:10.1038/nsmb1207-1122
Merging the RNA and DNA worlds
Irina Artsimovitch1 & Dmitry G Vassylyev1
- Irina Artsimovich is in the Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, USA. e-mail: artsimovitch.1@osu.edu
- Dmitry G. Vassylyev is in the Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Schools of Medicine and Dentistry, 402B Kaul Genetics Building, 720 20th Street South, Birmingham, Alabama 35294, USA. e-mail: dmitry@uab.edu
Abstract
The demonstrated ability of modern DNA-dependent RNA polymerases to use RNA templates for productive RNA synthesis suggests that they evolved from ancient RNA-dependent RNA replicases.
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RESEARCH
Molecular basis of RNA-dependent RNA polymerase II activityNature Letters to Editor (15 Nov 2007)
