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Chromatin structure depends on what's in the nucleosome's pocket

Two new studies point to a heretofore underappreciated mechanism by which chromatin higher-order structure can be regulated by surfaces in the nucleosome that are not associated with DNA.

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Figure 1: Multiple levels of chromatin structure.

Katie Ris-Vicari

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Caterino, T., Hayes, J. Chromatin structure depends on what's in the nucleosome's pocket. Nat Struct Mol Biol 14, 1056–1058 (2007). https://doi.org/10.1038/nsmb1107-1056

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