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Nature Structural & Molecular Biology 14, 885 - 887 (2007)
doi:10.1038/nsmb1007-885

Multienzyme assembly of a p53 transcription complex

Ted R Hupp1 & Malcolm Walkinshaw1

  1. Ted R. Hupp is at the Institute of Genetics and Molecular Medicine, Cancer Research UK p53 Signal Transduction Group, and Malcolm Walkinshaw is at the Institute for Translational and Chemical Biology, The University of Edinburgh, Edinburgh, EH4 2XR, UK. e-mail: ted.hupp@ed.ac.uk or e-mail: malcolm.walkinshaw@ed.ac.uk


Proline isomerization of the p53 transactivation domain has a central role in coordinating kinase signaling pathways that assemble the core p53 transcription complex.

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