News and Views

Nature Structural & Molecular Biology 14, 7 - 9 (2007)
doi:10.1038/nsmb0107-7

Insights into DNA deaminases

Silvestro G Conticello1, Marc-Andre Langlois1 & Michael S Neuberger1

  1. The authors are at the Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. e-mail: silvoc@mrc-lmb.cam.ac.uk or e-mail: msn@mrc-lmb.cam.ac.uk

The structures of APOBEC2 and TadA, members of a superfamily of Zn-dependent deaminases, reveal unexpected features and provide insight into the ability of some family members to act on DNA.

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