The author is in the Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 72205, USA. raneykevind@uams.edu
A new crystal structure reveals the path taken by single-stranded (ss) DNA through the central channel of a hexameric helicase. The path resembles a spiral staircase and provides an answer to the question of how hexameric helicases translocate on ssDNA.
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