Nature Structural & Molecular Biology 13, 380 - 381 (2006)
doi:10.1038/nsmb0506-380
Dancin' deaminaseReuben S Harris
& Hiroshi Matsuo
The authors are in the Department of Biochemistry, Molecular Biology and Biophysics and the Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, 55455, USA. rsh@umn.edu
New biochemical experiments with the retroelement restriction protein APOBEC3G indicate that it processively deaminates single-stranded DNA cytosines by a unique jumping and sliding mechanism.
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