Nature Structural & Molecular Biology 13, 297 - 299 (2006)
doi:10.1038/nsmb0406-297
oskar gains weightSean P Ryder
The author is in the Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, LRB-906, Worcester, Massachusetts, 01605, USA. sean.ryder@umassmed.edu
Posterior development in flies requires precise spatial regulation of Oskar translation. A recent report shows that Bruno controls Oskar translation by mediating the formation of large inert ribonucleoprotein particles that contain multiple copies of oskar messenger RNA. This work defines a new silencing mechanism and suggests a link between oskar translation control and localization.
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