Nature Structural & Molecular Biology 13, 209 - 217 (2006)
Published online: 19 February 2006; | doi:10.1038/nsmb1056
Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipidsDemet Araç, Xiaocheng Chen, Htet A Khant, Josep Ubach, Steven J Ludtke, Masahide Kikkawa, Arthur E Johnson, Wah Chiu, Thomas C Südhof
& Josep Rizo Supplementary Fig. 1 (pdf 691K) Problems with labeling C277 of synaptotagmin 1 Supplementary Fig. 2 (pdf 619K) Reconstruction of the oligomeric model of synaptotagmin 1 Supplementary Fig. 3 (pdf 1136K) Negative stain em analysis of synpatotagmin/calcium/lipid samples Supplementary Fig. 4 (pdf 227K) Synaptotagmin does not oligomerize Supplementary Fig. 5 (pdf 78K) Calcium dependence of synaptotagmin induced vesicle clustering Supplementary Fig. 6 (pdf 257K) Diverse considerations supporting the model of Figure 6
Supplementary Video 1 (mpg 2.2M) Tomographic 3D reconstruction of a vesicle cluster Supplementary Methods (pdf 17K)
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