Nature Structural & Molecular Biology 13, 190 - 192 (2006)
doi:10.1038/nsmb0306-190
Dicer measures upAtlanta Cook1
& Elena Conti21
The authors are at the European Molecular Biology Laboratory, Meyerhofstrasse 1, Heidelberg D-69117, Germany. 2
Elena Conti is also at the Max Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.
conti@embl.de
Recent structures of Dicer and the related bacterial enzyme, RNase III, demonstrate how Dicer acts as a molecular ruler, measuring out a precise length of double stranded RNA before cleavage.
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