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News and Views
Nature Structural & Molecular Biology 13, 98 - 99 (2006)
doi:10.1038/nsmb0206-98

Translation, interrupted

Tatyana V Pestova & Christopher U T Hellen

The authors are at the State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, New York 11203, USA. tatyana.pestova@downstate.edu

A recent study shows that the Drosophila melanogaster proapoptotic protein Reaper inhibits protein synthesis by direct binding to 40S ribosomal subunits, which affects recognition of initiation codons and ribosomal subunit joining.

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