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Journal home Advance online publication Current issue Archive Press releases Supplements Focus Guide to authors Online submission Permissions For referees Free online issue Contact the journal Subscribe Advertising work@npg naturereprints About this site For librarians   NPG Resources Nature Nature Cell Biology Nature Reviews Molecular Cell Biology The EMBO Journal Nature Reports Avian Flu NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Structural & Molecular Biology - 13, 1045 - 1047 (2006) doi:10.1038/nsmb1206-1045 Breaking up with a kinky SUMO Danny T Huang & Brenda A Schulman Danny T. Huang and Brenda A. Schulman are in the Howard Hughes Medical Institute and the Departments of Structural Biology & Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, MS #311, 332 N. Lauderdale, Memphis, Tennessee 38105, USA. brenda.schulman@stjude.org Ubiquitin-like protein (Ubl)-specific proteases catalyze Ubl precursor processing and deconjugation. Two recent structural studies of SUMO-specific protease (SENP)–substrate complexes provide new insight into hydrolysis of the peptide bond at the C terminus of SUMO. A kinked, cis configuration for the scissile bond is crucial for proteolysis. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated. NEWS AND VIEWS Beginning at the end with SUMO Nature Structural & Molecular Biology News and Views (01 Jul 2005) RESEARCH The structure of Atg4B?LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy The EMBO Journal Article (06 May 2009) SUMO protease SENP1 induces isomerization of the scissile peptide bond Nature Structural & Molecular Biology Article (01 Dec 2006) Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates Nature Structural & Molecular Biology Article (01 Dec 2006)  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Rights and permissions Order commercial reprints Save this link Figures & Tables See also: Article by Reverter & Lima See also: Article by Shen et al. Export citation Open Innovation Challenges Direct Molecular Detection of Proteins and Nucleic Acids Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id... Novel Approaches to Protecting Maize from Insect Damage Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re... More Challenges Powered by: nature jobs Environmental / Biotreatability Engineer Praj Matrix - Praj Industries Ltd Pune, Maharashtra Pune-411021 India Professor of Cognitive Neuroscience Karolinska Institute Stockholm Sweden More science jobs Post a job for free Search buyers guide:

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