Nature Structural & Molecular Biology 13, 5 - 7 (2006)
doi:10.1038/nsmb0106-5
Chromatin, transcript elongation and alternative splicingAlberto R Kornblihtt
The author is in the Departamento de Fisiología y Biología Molecular, LFBM and IFIByNE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón 2, (C1428EHA) Buenos Aires, Argentina. ark@fbmc.fcen.uba.ar
A recent study reveals that the chromatin-remodeling factor SWI/SNF regulates alternative splicing by creating internal 'roadblocks' to transcriptional elongation where the phosphorylation status of RNA pol II is qualitatively changed.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|