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News and Views
Nature Structural & Molecular Biology 13, 3 - 4 (2006)
doi:10.1038/nsmb0106-3

Drosha versus ADAR: wrangling over pri-miRNA

Mary A O'Connell & Liam P Keegan

The authors are in the MRC Human Genetic Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK. M.O'Connell@hgu.mrc.ac.uk

Processing of a mammalian hematopoietic microRNA precursor is suppressed when it is edited by ADARs. The edited pri-miRNA can subsequently be degraded by Tudor-SN.

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Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
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