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News and Views
Nature Structural & Molecular Biology  12, 734 - 736 (2005)
doi:10.1038/nsmb0905-734

Learning to unwind

James P J Chong

The author is in the Department of Biology (Area 5), University of York, PO Box 373, York YO10 5YW, UK. jpjc1@york.ac.uk

DNA helicases unwind DNA by a number of mechanisms in which conformational change seems to be of central importance. Characterization of two beta-hairpins and fluorescence resonance energy transfer studies of protein-DNA interactions in the minichromosome maintenance proteins afford new insights into the molecular mechanisms of these proteins.

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Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
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