Spliceosome assembly in yeast: one ChIP at a time?
Timothy W Nilsen
The author is at the Center for RNA Molecular Biology, Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, Ohio 44106-4973, USA. twn@cwru.edu
When and how the spliceosome assembles on its substrates in living yeast cells has been unclear. It is now evident that the 'when' is during transcription; the 'how' remains debatable.
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