MicroRNAs have established roles in negatively regulating messenger RNAs. Two plant microRNAs have recently been shown to target certain non-protein-coding RNAs for cleavage, adding a new dimension to the known roles of these tiny riboregulators.
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Acknowledgements
I thank D. Bartel, D. Dugas and A. Woodward for comments on the manuscript. MicroRNA research is supported in the author's laboratory by the US National Institutes of Health (R24-GM069512), the G. Harold and Leila Y. Mathers Charitable Foundation and the Robert A. Welch Foundation (C-1309).
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Bartel, B. MicroRNAs directing siRNA biogenesis. Nat Struct Mol Biol 12, 569–571 (2005). https://doi.org/10.1038/nsmb0705-569
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DOI: https://doi.org/10.1038/nsmb0705-569
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