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News and Views
Nature Structural & Molecular Biology  12, 474 - 475 (2005)
doi:10.1038/nsmb0605-474

The end justifies the means

Allan Jacobson

The author is in the Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655-0122, USA.
allan.jacobson@umassmed.edu

Translation termination, once thought to be the least complex of the steps in protein synthesis, is emerging as a process subject to considerable regulation. The prevalent mode for this regulation seems to be eRF-tweaking, the modulation of release factor activity by proteins involved in other gene expression pathways.

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Open Innovation Challenges

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Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
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