The authors are in the Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA. lgavis@molbio.princeton.edu
A recent study links the double-stranded RNA-binding protein Staufen (Stau) 1 and the nonsense-mediated decay factor Upf1 in a novel mRNA decay pathway. Stafen now dons two hats to participate in two different pathways—one that directs mRNA localization and one that directs mRNA decay.
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