The author is at the National Institute of Child Health and Human Development, Building 35, Room 3B1002, Bethesda, Maryland 20892, USA. mlm@helix.nih.gov
Glutamate receptor ion channels are multidomain membrane proteins that mediate excitatory synaptic responses in the brain and spinal cord. Single-particle electron microscopy reveals their molecular envelope and how this changes during desensitization.
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