Nature Structural & Molecular Biology
12, 826 - 829 (2005)
doi:10.1038/nsmb1005-826
Intracellular RNA sorting, transport and localizationRalf-Peter Jansen
& Michael Kiebler
R.-P. J. is at the Gene Center LMU, University of Munich, Foedor-Lynen-Str. 25, D-81377 Munich, Germany. M.K. is at the Center for Brain Research, Department of Neuronal Cell Biology, Medical University of Vienna, Spitalgasse 4, A-1090 Vienna, Austria. rjansen@lmb.uni-muenchen.de or michael.kiebler@meduniwien.ac.at
RNA localization and translational control are crucial for cellular fine-tuning of gene expression in space and time. A recent meeting in Tucson, Arizona pointed out mechanisms conserved across different species and cell types that contribute to the establishment of cell polarity and cell migration. Furthermore, it is becoming increasingly clear that these post-transcriptional control processes are relevant for various diseases.
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