The authors are in the Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA reid.gilmore@umassmed.edu
Two recent structural studies on the GTPases of the bacterial signal recognition particle−receptor complex reveal how direct interactions between the two ribonucleotides in a shared GTP-binding cavity contribute to the assembly and the GTPase-activated disassembly of this targeting complex.
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