1
Bazbek Davletov is in the MRC Laboratory of Molecular Biology, Cambridge, UK. baz@mrc-lmb.cam.ac.uk
2
José L. Jiménez is in the Biomolecular Modelling Laboratory, Cancer Research UK London Research Institute, London, UK. jimenez@cancer.org.uk
A recent study demonstrates that a short insert from alternative splicing in a common protein domain leads to rearrangements of surface loops and domain fold. The results provide a structural basis for the change of functional properties associated with alternative splicing.
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